Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507342 | 0.87 | GAA (0.72) | GAAKMT2ANR5A2NR5A1MEN1 | |
| SCHEMBL10360929 | 0.83 | GAA (0.70) | GAAKMT2ANR5A2NR5A1HTT | |
| SCHEMBL9575245 | 0.81 | GAA (0.64) | GAAKMT2ANR5A2NR5A1MEN1 | |
| SCHEMBL28834940 | 0.81 | GAA (0.67) | GAAKMT2ANR5A2NR5A1MEN1 | |
| SCHEMBL22540664 | 0.78 | GAA (0.51) | GAAKMT2APKMHTTMEN1 | |
| SCHEMBL9575255 | 0.77 | GAA (0.59) | GAAKMT2ANR5A2NR5A1MEN1 | |
| SCHEMBL11506250 | 0.77 | GAA (0.54) | GAAKMT2ANR5A2NR5A1HTT | |
| SCHEMBL11557692 | 0.77 | GAA (0.52) | GAAKMT2APKMHTTMEN1 | |
| SCHEMBL24140175 | 0.77 | GAA (0.50) | GAAKMT2APKMHTTMEN1 | |
| SCHEMBL8944855 | 0.76 | ALDH1A1 (0.57) | GAAPKMHTTHMGCRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |