Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275814 | 0.96 | ALDH1A1 (0.56) | ALDH1A1GAATDP1MAPTGPR35 | |
| SCHEMBL8944759 | 0.84 | ALDH1A1 (0.64) | ALDH1A1GAATDP1MAPTGPR35 | |
| SCHEMBL8944807 | 0.78 | GAA (0.53) | ALDH1A1GAATDP1MAPTPKM | |
| SCHEMBL11517292 | 0.77 | MAPT (0.52) | ALDH1A1GAATDP1MAPTPKM | |
| SCHEMBL9812317 | 0.77 | GAA (0.68) | ALDH1A1GAATDP1MAPTGPR35 | |
| SCHEMBL4574900 | 0.77 | GPR35 (0.49) | ALDH1A1GAAMAPTGPR35PKM | |
| SCHEMBL295404 | 0.77 | ALDH1A1 (0.72) | ALDH1A1GAATDP1MAPTHTT | |
| SCHEMBL9575290 | 0.76 | GAA (0.61) | ALDH1A1GAATDP1MAPTPKM | |
| SCHEMBL3483031 | 0.76 | GAA (0.66) | ALDH1A1GAATDP1MAPTRAB9A | |
| SCHEMBL4290190 | 0.75 | MAPT (0.67) | ALDH1A1GAATDP1MAPTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578731-A | ASYMMETRICAL HYDRAZINE DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| US-5554754-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5470980-A | Light stabilizers for polymers that can be grafted to polymers | CIBA-GEIGY CORPORATION (US) | 1995-11-28 | — | — | US | disclosed |
| US-5352719-A | Blended with synthetic or natural polymers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-5319090-A | Benzotriazole and oxanilide UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5233047-A | Benzotriazole UV absorber hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5116976-A | HINDERED AMINE LIGHT STABILIZER HYDRAZIDES | ATOCHEM NORTH AMERICA, INC (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0467344-A1 | Hindered amine light stabilizer hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5041545-A | 2-hydroxybenzophenone hydrazides and derivatives thereof | ATOCHEM NORTH AMERICA, INC. (US) | 1991-08-20 | — | — | US | disclosed |
| US-4980420-A | Benzotriazole and oxanilide UV absorber hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4801749-A | Phenolic antioxidant hydrazides | PENNWALT CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |