Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575545 | 0.98 | NPC1 (0.38) | NPC1KDM4EPRMT5WDR77 | |
| SCHEMBL9575677 | 0.88 | KDM4E (0.30) | KDM4E | |
| SCHEMBL9575787 | 0.87 | KDM4E (0.32) | NPC1KDM4E | |
| SCHEMBL9019792 | 0.80 | EPHX1 (0.31) | KDM4E | |
| SCHEMBL9197811 | 0.78 | EPHX1 (0.33) | KDM4E | |
| SCHEMBL8077669 | 0.70 | NPC1 (0.37) | NPC1KDM4EPRMT5WDR77 | |
| SCHEMBL6178354 | 0.70 | NPC1 (0.44) | NPC1 | |
| SCHEMBL16004201 | 0.70 | NPC1 (0.38) | NPC1KDM4EPRMT5WDR77 | |
| SCHEMBL16004199 | 0.70 | NPC1 (0.38) | NPC1KDM4EPRMT5WDR77 | |
| SCHEMBL22692803 | 0.69 | USP2 (0.37) | KDM4EPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |