Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019792 | 0.98 | EPHX1 (0.31) | EPHX1KDM4E | |
| SCHEMBL2739883 | 0.81 | EPHX1 (0.40) | EPHX1ALDH1A1NAAACYP19A1HTT | |
| SCHEMBL24603593 | 0.81 | EPHX1 (0.40) | EPHX1ALDH1A1NAAACYP19A1HTT | |
| SCHEMBL9575545 | 0.80 | NPC1 (0.38) | KDM4EALDH1A1MAPTHTT | |
| SCHEMBL2739881 | 0.79 | EPHX1 (0.37) | EPHX1ALDH1A1NAAAHTT | |
| SCHEMBL9575317 | 0.78 | NPC1 (0.34) | KDM4E | |
| SCHEMBL22845686 | 0.77 | KDM4E (0.43) | EPHX1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL9575787 | 0.75 | KDM4E (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL2466001 | 0.74 | TDP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL9575677 | 0.73 | KDM4E (0.30) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448006-B1 | Process for the preparation of acylales | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5231221-A | PROCESS FOR THE PREPARATION OF ACYLALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0448006-A2 | Process for the preparation of acylales | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |