Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.80 |
| ▸ | MAOA | P21397 | 3/20 | 0.80 |
| ▸ | MAOB | P27338 | 3/20 | 0.80 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | PDE6A | P16499 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyzoline SCHEMBL3172677 | 0.89 | NISCH (1.00) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL7518582 | 0.88 | NISCH (0.67) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL17350092 | 0.84 | MAOA (0.57) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL12495025 | 0.83 | RAD52 (0.57) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL5350249 | 0.83 | NISCH (0.56) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL23097221 | 0.83 | HTR1D (0.60) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL9575185 | 0.82 | NISCH (0.55) | NISCHMAOAMAOBTAAR1LMNA | |
| SCHEMBL3168522 | 0.82 | NISCH (0.73) | NISCHMAOAMAOBTAAR1LMNA | |
| Tolazoline SCHEMBL34869 | 0.81 | TAAR1 (1.00) | NISCHMAOAMAOBTAAR1LMNA | |
| Tolazoline SCHEMBL5053858 | 0.81 | TAAR1 (1.00) | NISCHMAOAMAOBTAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183369-A1 | NEURITE OUTGROWTH PROMOTERS AND USES THEREOF | UNIVERSITY OF MIAMI (US) | 2019-09-26 | — | — | WO | disclosed |
| EP-0331507-B1 | POLYVINYL CHLORIDE PLASTISOL COMPOSITION | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4977201-A | Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings | ASAHI DENKA KOGYO K.K. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0331507-A1 | Polyvinyl chloride plastisol composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |