Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274802 | 0.86 | IGFBP3 (0.43) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL28608865 | 0.82 | PLAU (0.60) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL4726584 | 0.81 | IGFBP3 (0.47) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL756471 | 0.81 | KDM4E (0.47) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL13258529 | 0.81 | PLAU (0.41) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL755956 | 0.81 | KMO (0.42) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL11374392 | 0.80 | IGFBP3 (0.64) | IGFBP3KDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL755949 | 0.77 | PLAU (0.57) | PLAUKDM4EASPHKDM8LMNA | |
| SCHEMBL15844723 | 0.77 | PLAU (0.46) | IGFBP3PLAUKDM4EASPHKDM8 | |
| SCHEMBL13153181 | 0.77 | PLAU (0.38) | IGFBP3PLAUKDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5310705-A | — | — | None | — | — | JP | disclosed |
| JP-H05310705-A | NEW ISOQUINOLINECARBOXYLIC ACID DERIVATIVE | SNOW BRAND MILK PROD CO LTD | 1993-11-22 | — | — | JP | disclosed |