Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 12/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 12/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 12/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 12/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 12/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 12/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796040 | 1.00 | MEN1 (0.41) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL964013 | 0.91 | MEN1 (0.40) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL30794749 | 0.86 | KCNQ3 (0.41) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL30794397 | 0.86 | KCNQ3 (0.51) | MEN1KMT2AKCNQ3KCNQ2CACNA1H | |
| SCHEMBL954416 | 0.86 | KCNQ3 (0.41) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL953813 | 0.86 | KCNQ3 (0.51) | MEN1KMT2AKCNQ3KCNQ2CACNA1H | |
| SCHEMBL955731 | 0.84 | MEN1 (0.40) | MEN1KMT2AKCNQ3KCNQ2CACNA1H | |
| SCHEMBL953928 | 0.84 | MEN1 (0.40) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL30796708 | 0.84 | MEN1 (0.40) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL30795463 | 0.78 | KCNQ2 (0.44) | MEN1KMT2APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003865-A1 | NOVEL 2-DIETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS | NEUROSEARCH A/S (DK) | 2011-01-06 | — | — | US | claimed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |
| US-20110003865-A1 | NOVEL 2-DIETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS | NEUROSEARCH A/S (DK) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003865-A1 | NOVEL 2-DIETHYLAMINO-3-AMIDO-6-AMINO-PYRIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL ACTIVATORS | KCNA7, KCNN3, KCNJ2 | MEN1 1888/4885KMT2A 940/4885PSEN1 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.