⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988663 | 0.82 | — | — | |
| SCHEMBL9575564 | 0.80 | — | — | |
| SCHEMBL9019769 | 0.73 | — | — | |
| SCHEMBL9575513 | 0.73 | — | — | |
| SCHEMBL9575515 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL20438401 | 0.68 | — | — | |
| SCHEMBL9845276 | 0.67 | — | — | |
| SCHEMBL9575428 | 0.67 | HSD17B10 (0.45) | — | |
| SCHEMBL20438457 | 0.67 | — | — | |
| SCHEMBL818625 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |