⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575513 | 0.89 | — | — | |
| SCHEMBL9575515 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL9575502 | 0.82 | — | — | |
| SCHEMBL9575428 | 0.82 | HSD17B10 (0.45) | — | |
| SCHEMBL9575549 | 0.80 | LPAR1 (0.40) | — | |
| SCHEMBL25459932 | 0.79 | LMNA (0.45) | — | |
| SCHEMBL24858363 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL9575543 | 0.78 | CA1 (0.38) | — | |
| SCHEMBL20438401 | 0.78 | — | — | |
| SCHEMBL9575677 | 0.77 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589335-B1 | N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means | HOECHST AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-5457091-A | N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |