Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL9794795 | 0.91 | FABP3 (0.51) | FABP3SLC6A5FAAHGMNNUSP2 | |
| Glycine SCHEMBL9575926 | 0.90 | FABP3 (0.50) | FABP3SLC6A5FAAHCYP1A2CYP2C19 | |
| SCHEMBL9575939 | 0.88 | FAAH (0.44) | FAAHTERTGMNNUSP2LMNA | |
| Formic Acid SCHEMBL9794876 | 0.87 | FAAH (0.46) | FABP3FAAHTERTGMNNUSP2 | |
| Hydrochloric Acid SCHEMBL9575650 | 0.86 | FAAH (0.42) | FAAHTERTGMNNUSP2LMNA | |
| Cysteine SCHEMBL9575905 | 0.82 | FABP3 (0.41) | FABP3SLC6A5FAAHCYP1A2CYP2C19 | |
| Oleic Acid SCHEMBL26929136 | 0.78 | FABP3 (0.89) | FABP3FAAHTERTGMNNUSP2 | |
| Oleic Acid SCHEMBL107190 | 0.78 | FABP3 (0.89) | FABP3FAAHTERTGMNNUSP2 | |
| Oleic Acid SCHEMBL107188 | 0.78 | FABP3 (0.89) | FABP3FAAHTERTGMNNUSP2 | |
| Oleic Acid SCHEMBL28686398 | 0.78 | FABP3 (0.75) | FABP3SLC6A5TERTGMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371406-B1 | OXYALKYLATED QUATERNARY AMMONIUM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID COMPOUNDS | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5076828-A | Immersing seeds into quaternary solution prior to planting | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0371406-A1 | Oxyalkylated quaternary ammonium compounds, processes for production thereof, and plant growth regulating compositions containing said compounds | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |