Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL9794795 | 0.90 | FABP3 (0.51) | FABP3FAAHCYP1A2CYP2C19SLC6A5 | |
| Succinic Acid SCHEMBL9575747 | 0.90 | FABP3 (0.59) | FABP3FAAHCYP1A2CYP2C19SLC6A5 | |
| SCHEMBL9575939 | 0.87 | FAAH (0.44) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Formic Acid SCHEMBL9794876 | 0.85 | FAAH (0.46) | FABP3FAAHCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9575650 | 0.85 | FAAH (0.42) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Cysteine SCHEMBL9575905 | 0.83 | FABP3 (0.41) | FABP3FAAHSOAT1MEN1TP53 | |
| SCHEMBL9575956 | 0.76 | SPHK1 (0.45) | TP53 | |
| Cadaverine Tartrate SCHEMBL9575895 | 0.76 | FFAR1 (0.48) | FABP3FAAHCYP1A2CYP2C19KMT2A | |
| Aspartic Acid SCHEMBL9575855 | 0.76 | CA1 (0.44) | MEN1TP53CYP3A4CYP2C19KMT2A | |
| SCHEMBL4409622 | 0.76 | FABP3 (0.44) | FABP3FAAHCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2145551-A | — | — | None | — | — | JP | disclosed |
| EP-0371406-B1 | OXYALKYLATED QUATERNARY AMMONIUM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID COMPOUNDS | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5076828-A | Immersing seeds into quaternary solution prior to planting | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0371406-A1 | Oxyalkylated quaternary ammonium compounds, processes for production thereof, and plant growth regulating compositions containing said compounds | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| JP-H02145551-A | NOVEL OXYALKYLATED QUATERNARY AMMONIUM COMPOUND, PRODUCTION THEREOF AND PLANT GROWTH REGULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | DAI ICHI KOGYO SEIYAKU CO LTD | 1990-06-05 | — | — | JP | disclosed |