Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.57 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185722 | 0.90 | PKM (0.65) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL15828724 | 0.83 | HCAR3 (0.61) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL9395556 | 0.80 | HCAR3 (0.64) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL7191754 | 0.79 | PKM (0.61) | HCAR3WNK1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7191751 | 0.79 | PKM (0.61) | HCAR3WNK1ALDH1A1MAPTMAPK1 | |
| SCHEMBL23786250 | 0.78 | MAPT (0.69) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL8607686 | 0.78 | MAPT (0.69) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL2687698 | 0.78 | PKM (0.63) | HCAR3WNK1ALDH1A1MAPTMAPK1 | |
| SCHEMBL1925077 | 0.77 | HCAR3 (0.61) | HCAR3WNK1ALDH1A1MAPTLMNA | |
| SCHEMBL7178280 | 0.77 | PKM (0.62) | HCAR3WNK1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278414-B1 | PROCESS FOR THE PREPARATION OF REACTION PRODUCTS OF 2,2-BIS (4-HYDROXYPHENYL) HEXAFLUOROPROPANE, AND THE DERIVATIVES OBTAINED | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5028728-A | Process for the preparation of reaction products of 2,2-bis-(4-hydroxphenyl)-hexafluoropropane and new derivatives of this type | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0278414-A2 | Process for the preparation of reaction products of 2,2-bis (4-hydroxyphenyl) hexafluoropropane, and the derivatives obtained | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |