Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575586 | 0.99 | ALDH1A1 (0.48) | ALDH1A1GAATSHRCA12CA1 | |
| SCHEMBL11851628 | 0.79 | GAA (0.49) | ALDH1A1GAATSHRCA12CA1 | |
| SCHEMBL9202081 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL8752459 | 0.77 | CA12 (0.47) | ALDH1A1GAATSHRCA12CA1 | |
| SCHEMBL1685394 | 0.75 | BRD4 (0.51) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL10913560 | 0.74 | GAA (0.56) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL8971922 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAATSHRCA12CA1 | |
| SCHEMBL9176780 | 0.74 | ALDH1A1 (0.45) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL9178665 | 0.74 | ALDH1A1 (0.45) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| SCHEMBL9175306 | 0.74 | ALDH1A1 (0.45) | ALDH1A1GAATSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| EP-0258183-A2 | Process for the preparation of 5-amino-4-hydroxyvaleric-acid derivatives | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |