SCHEMBL95759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17888367	0.86	MAPT (0.68)	NAMPTALDH1A1POLBMAPTHTT
	SCHEMBL17886718	0.83	ALDH1A1 (0.59)	NAMPTALDH1A1POLBMAPTHTT
	SCHEMBL95296	0.83	SMN1; SMN2 (0.67)	NAMPTALDH1A1POLBSMN1; SMN2MEN1
	SCHEMBL94420	0.83	MEN1 (0.74)	ALDH1A1POLBMAPTMEN1KMT2A
	SCHEMBL27781454	0.79	TRPV1 (0.56)	NAMPTALDH1A1AKR1C3TRPV1
	SCHEMBL21987023	0.79	MAPT (0.69)	NAMPTALDH1A1POLBMAPTHTT
	SCHEMBL94351	0.78	SLC6A7 (0.73)	NAMPTALDH1A1MEN1KMT2ASLC6A7
	SCHEMBL1981285	0.78	TRPV1 (0.55)	NAMPTALDH1A1TRPV1
	SCHEMBL94316	0.78	KDM4E (0.61)	ALDH1A1HTTMEN1KMT2AFNTA
	SCHEMBL2377185	0.78	ALDH1A1 (0.57)	NAMPTALDH1A1MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.