Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | DAGLB | Q8NCG7 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576484 | 1.00 | DAGLA (0.35) | DAGLACNR1DAGLBMGLLPRKCA | |
| SCHEMBL9718248 | 0.88 | DAGLA (0.36) | DAGLACNR1DAGLBMGLLPRKCA | |
| SCHEMBL9718250 | 0.88 | DAGLA (0.36) | DAGLACNR1DAGLBMGLLPRKCA | |
| SCHEMBL10367940 | 0.75 | PRKCA (0.41) | DAGLACNR1DAGLBMGLLPRKCA | |
| SCHEMBL9580585 | 0.74 | — | — | |
| Antibiotic 1233A SCHEMBL613745 | 0.74 | PRKCA (0.35) | DAGLACNR1DAGLBMGLLPRKCA | |
| Antibiotic 1233A SCHEMBL285680 | 0.74 | PRKCA (0.35) | DAGLACNR1DAGLBMGLLPRKCA | |
| Antibiotic 1233A SCHEMBL285679 | 0.74 | PRKCA (0.35) | DAGLACNR1DAGLBMGLLPRKCA | |
| SCHEMBL9825431 | 0.73 | DAGLA (0.38) | DAGLACNR1DAGLBPRKCAPRKD3 | |
| SCHEMBL5495024 | 0.72 | PRKCA (0.38) | DAGLACNR1DAGLBMGLLPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214067-A | Mixture of pyranyl glycine ester and beta-lactone | MERCK & CO., INC. (US) | 1993-05-25 | — | — | US | claimed |
| EP-0479356-A1 | Fungicidal compositions and method | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | claimed |
| US-4988697-A | Alpha-demethylase inhibiting azole compound and a beta-lactone | MERCK & CO., INC. (US) | 1991-01-29 | — | — | US | claimed |
| US-4920113-A | TO ERADICATE MYCOTIC INFECTIONS; NONTOXIC, SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 1990-04-24 | — | — | US | claimed |
| EP-0339708-A2 | Fungicidal compositions and method | MERCK & CO. INC. (US) | 1989-11-02 | — | — | EP | claimed |
| JP-1311025-A | — | — | None | — | — | JP | disclosed |
| US-5214067-A | Mixture of pyranyl glycine ester and beta-lactone | MERCK & CO., INC. (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0339709-B1 | ANTIFUNGAL COMPOSITIONS AND METHOD OF CONTROLLING MYCOTIC INFECTIONS | MERCK & CO. INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0479356-A1 | Fungicidal compositions and method | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| US-4988697-A | Alpha-demethylase inhibiting azole compound and a beta-lactone | MERCK & CO., INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4921844-A | 25-AZASTEROLS, B-KETOTHIOLASE INHIBITORS | MERCK & CO., INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4920111-A | SYNERGISTIC | MERCK & CO., INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4920109-A | COADMINISTERING A 25-AZASTEROL WITH A NON-STEROIDAL AGENT; NONTOXIC, SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4920113-A | TO ERADICATE MYCOTIC INFECTIONS; NONTOXIC, SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4920112-A | SYNERGISTIC 25-AZASTEROL COMPOUND AND SQUALENE EPOXIDASE INHIBITOR | MERCK & CO., INC. (US) | 1990-04-24 | — | — | US | disclosed |
| JP-H01311025-A | FUNGICIDAL COMPOSITION AND METHOD | MERCK & CO INC | 1989-12-15 | — | — | JP | disclosed |
| EP-0339709-A2 | Antifungal compositions and method of controlling mycotic infections | MERCK & CO. INC. (US) | 1989-11-02 | — | — | EP | disclosed |
| EP-0339708-A2 | Fungicidal compositions and method | MERCK & CO. INC. (US) | 1989-11-02 | — | — | EP | disclosed |