Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261326 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL25525586 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL14281899 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL15341681 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL6368625 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL6568086 | 0.78 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL27821808 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL19847358 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL301798 | 0.76 | ALDH1A1 (0.68) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL8851631 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | claimed |
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |