Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457415 | 1.00 | F2 (0.42) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL10456633 | 1.00 | F2 (0.42) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL10706898 | 0.87 | SCN9A (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11463251 | 0.87 | MEN1 (0.41) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL11362023 | 0.87 | NPC1 (0.39) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL11377767 | 0.87 | L3MBTL1 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL13726918 | 0.87 | F2 (0.38) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL10548769 | 0.84 | F2 (0.41) | F2F10TSHRPRSS1PRSS2 | |
| SCHEMBL11174821 | 0.84 | MAP4K4 (0.44) | F2F10MAP4K4HSD17B14ALDH1A1 | |
| SCHEMBL11172123 | 0.84 | KDM4E (0.42) | F2F10TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132392-B1 | ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS | ICI AUSTRALIA LIMITED (AU) | 1992-01-02 | — | — | EP | claimed |
| EP-0082049-B1 | ETHERS WITH CHIRAL ATOMS IN THE ORGANIC REST GROUPS, THEIR PREPARATION, THEIR USE IN THE RESOLUTION OF ALCOHOLS OR OF CERTAIN HEMIACETALS, AND COMPOUNDS SO RESOLVED | ROUSSEL-UCLAF (FR) | 1987-07-29 | — | — | EP | claimed |
| US-4661488-A | Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-28 | — | — | US | claimed |
| US-4582856-A | INSECXTICIDE, ACARICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-15 | — | — | US | claimed |
| EP-0162538-A2 | Cyclopropane derivates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-27 | — | — | EP | claimed |
| US-4256893-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | claimed |
| US-5245073-A | Pesticides, insecticides, hydrogenation | ROUSSEL UCLAF (FR) | 1993-09-14 | — | — | US | disclosed |
| US-5082832-A | Pesticides | ROUSSEL UCLAF (FR) | 1992-01-21 | — | — | US | disclosed |
| US-5049585-A | Certain 3,3-bis-(difluoro methyl)2,2-dimethyl-cyclopropane carboxylates having insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |
| US-4935532-A | Hemiacetals | ROUSSEL UCLAF (FR) | 1990-06-19 | — | — | US | disclosed |
| US-4925874-A | INSECTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |
| EP-0364116-A1 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-18 | — | — | EP | disclosed |
| US-4898968-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-06 | — | — | US | disclosed |
| US-4238614-A | Pyridyl esters of ether and thioether substituted cyclopropanecarboxylic acids | ZOECON CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4228172-A | Substituted pyridine methyl esters of 2-isopropyl-2-(4-chlorophenyl)acetic acid and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4224330-A | Esters and thiolesters of benzothienyl acids | ZOECON CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4223033-A | Substituted pyridine methyl esters of naphthyl acids | ZOECON CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4221799-A | MITICIDES | THE DOW CHEMICAL (US) | 1980-09-09 | — | — | US | disclosed |
| US-4163787-A | Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |