Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457415 | 0.84 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL9577109 | 0.84 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10456633 | 0.84 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL11360231 | 0.82 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10548446 | 0.79 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL9270503 | 0.79 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL9818071 | 0.79 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8972394 | 0.76 | F2 (0.43) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL2521152 | 0.75 | LTA4H (0.58) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10720414 | 0.75 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256893-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | claimed |
| JP-56092249-A | — | — | None | — | — | JP | disclosed |
| US-4833163-A | INSECTICIDES, NEMATOCIDES, MITICIDES | ROUSSEL UCLAF (FR) | 1989-05-23 | — | — | US | disclosed |
| US-4584304-A | INSECTICIDE, PESTICIDE | SHELL OIL COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4281133-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| JP-S5692249-A | NOVEL CARBOXYLIC ESTER, ITS PREPARATION AND INSECTICIDE, ACARICIDE | NISSAN CHEM IND LTD | 1981-07-25 | — | — | JP | disclosed |
| US-4256893-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4248875-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4223033-A | Substituted pyridine methyl esters of naphthyl acids | ZOECON CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4163787-A | Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |