Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546726 | 0.84 | KDM4E (0.30) | — | |
| SCHEMBL6546850 | 0.81 | — | — | |
| SCHEMBL11294413 | 0.80 | SMN1; SMN2 (0.32) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27564196 | 0.74 | SMN1; SMN2 (0.33) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21851596 | 0.72 | CTBP2 (0.37) | — | |
| SCHEMBL1785876 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL1785041 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL28283127 | 0.71 | OPRM1 (0.35) | SLC6A2SLC6A3 | |
| SCHEMBL7340572 | 0.70 | HTT (0.33) | SLC6A3 | |
| SCHEMBL29987487 | 0.70 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245073-A | Pesticides, insecticides, hydrogenation | ROUSSEL UCLAF (FR) | 1993-09-14 | — | — | US | disclosed |
| US-5082832-A | Pesticides | ROUSSEL UCLAF (FR) | 1992-01-21 | — | — | US | disclosed |
| US-4925874-A | INSECTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |