Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.75 |
| ▸ | TP53 | P04637 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | TSHR | P16473 | 4/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | FPR2 | P25090 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577190 | 0.98 | CYP3A4 (0.72) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL9577122 | 0.87 | CYP3A4 (0.62) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL31014182 | 0.86 | CYP3A4 (0.72) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL9577185 | 0.86 | RECQL (0.74) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL29653788 | 0.86 | CYP3A4 (1.00) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL317323 | 0.86 | CYP3A4 (1.00) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL10455056 | 0.85 | ALDH1A1 (0.63) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL13296442 | 0.81 | CYP3A4 (0.65) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL9309072 | 0.81 | RECQL (0.62) | CYP3A4CYP1A2CYP2C19TP53MEN1 | |
| SCHEMBL1287486 | 0.78 | CYP1A2 (0.68) | CYP3A4CYP1A2CYP2C19TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |