Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518646 | 0.83 | CA1 (0.56) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL29558069 | 0.83 | CA1 (0.56) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL29452062 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL2782423 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL7215374 | 0.78 | TDP1 (0.38) | ALDH1A1POLBCA2CA1CA4 | |
| SCHEMBL4021727 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL4665197 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL11174948 | 0.77 | MCL1 (0.50) | ALDH1A1SMN1; SMN2HTTPOLBCA2 | |
| SCHEMBL10605529 | 0.76 | CA2 (0.50) | CA2CA1CA4CA6PLCG1 | |
| SCHEMBL8854263 | 0.75 | POLB (0.42) | ALDH1A1SMN1; SMN2HTTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |