Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198396 | 0.93 | TSHR (0.67) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL6401230 | 0.80 | TSHR (0.49) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL6395244 | 0.79 | TSHR (0.45) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL6394290 | 0.77 | KDM4E (0.47) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL197625 | 0.76 | TSHR (0.58) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL11334245 | 0.74 | ALDH1A1 (0.49) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL7220988 | 0.74 | GSTO1 (0.45) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL198462 | 0.74 | NPSR1 (0.43) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL3012009 | 0.73 | TSHR (0.59) | TSHRSMN1; SMN2LMNAKDM4ETP53 | |
| SCHEMBL13576549 | 0.72 | MAPT (0.62) | TSHRSMN1; SMN2LMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |