Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 14/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503762 | 0.85 | AKR1C1 (0.68) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL694700 | 0.83 | AKR1C1 (0.66) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| Hydrochloric Acid SCHEMBL5741878 | 0.83 | AKR1C1 (0.66) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL6673357 | 0.82 | AKR1C1 (0.70) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL9577294 | 0.81 | AKR1C1 (0.48) | HDAC4HSD11B1ALDH1A1AKR1C1 | |
| SCHEMBL6672119 | 0.81 | AKR1C1 (0.68) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL1794 | 0.81 | AKR1C1 (0.62) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL1627734 | 0.81 | HDAC4 (0.66) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL4805246 | 0.79 | HDAC4 (0.64) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 | |
| SCHEMBL5862774 | 0.79 | HDAC4 (0.64) | HDAC4HSD11B1ALDH1A1AKR1C1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |