Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048151 | 0.85 | AKR1C1 (0.68) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL2860893 | 0.83 | AKR1C1 (0.66) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL3821416 | 0.83 | AKR1C1 (0.66) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL6673357 | 0.82 | AKR1C1 (0.70) | AKR1C1NPSR1MEN1KMT2AHDAC4 | |
| SCHEMBL9577271 | 0.81 | HDAC4 (0.62) | AKR1C1HDAC4ALDH1A1HSD11B1 | |
| SCHEMBL2443314 | 0.81 | MAPT (0.49) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL3485961 | 0.81 | AKR1C1 (0.62) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL6672119 | 0.81 | AKR1C1 (0.68) | AKR1C1NPSR1MEN1KMT2AHDAC4 | |
| SCHEMBL6202789 | 0.79 | LMNA (0.57) | AKR1C1MAPTHTR1ENPSR1S1PR3 | |
| SCHEMBL11282279 | 0.79 | MAPT (0.48) | AKR1C1MAPTHTR1ENPSR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |