Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626481 | 0.85 | AKR1C3 (0.51) | TSHRSSTR4CYP2C19HDAC3HDAC1 | |
| SCHEMBL602699 | 0.81 | TSHR (0.48) | TSHRSSTR4CYP2C19HDAC3HDAC1 | |
| SCHEMBL1627092 | 0.81 | TSHR (0.48) | TSHRSSTR4CYP2C19HDAC3HDAC1 | |
| SCHEMBL8443184 | 0.79 | KMT2A (0.52) | TSHRSSTR4CYP2C19HDAC3HDAC1 | |
| SCHEMBL6671431 | 0.79 | KMT2A (0.50) | TSHRCYP2C19SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6671026 | 0.77 | CES2 (0.40) | SMN1; SMN2KMT2ANPC1RAB9ACYP19A1 | |
| SCHEMBL6670810 | 0.76 | KIF11 (0.42) | CYP2C19SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1627157 | 0.76 | CNR1 (0.51) | TSHRSSTR4CYP2C19HDAC3HDAC1 | |
| SCHEMBL30443832 | 0.76 | TSHR (0.44) | TSHRSSTR4HDAC3HDAC1HDAC2 | |
| SCHEMBL2348384 | 0.76 | TSHR (0.47) | TSHRSSTR4CYP2C19HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |