Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373017 | 0.93 | HMGCR (0.39) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9577567 | 0.91 | HMGCR (0.49) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9577647 | 0.79 | MTNR1A (0.34) | CYP2C9MMP12MEN1KMT2A | |
| SCHEMBL9577656 | 0.79 | MTNR1A (0.34) | CYP2C9MMP12MEN1KMT2A | |
| SCHEMBL9577560 | 0.72 | HMGCR (0.40) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9845365 | 0.72 | HMGCR (0.49) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9577596 | 0.72 | HMGCR (0.49) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9845362 | 0.72 | HMGCR (0.49) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9577746 | 0.71 | HMGCR (0.49) | HMGCRCYP2C9SIRT6NR4A2PDE4D | |
| SCHEMBL9577623 | 0.70 | HMGCR (0.40) | HMGCRCYP2C9SIRT6NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183924-A | Anticholesterol agents, antithrombotics, fungicides | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-02-02 | — | — | US | disclosed |
| US-5082859-A | Anticholesterol, anticoagulant, fungicide | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-01-21 | — | — | US | disclosed |