Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577647 | 1.00 | MTNR1A (0.34) | MTNR1AMTNR1BL3MBTL1POLBALDH1A1 | |
| SCHEMBL9373017 | 0.85 | HMGCR (0.39) | CYP2C9MMP12 | |
| SCHEMBL9577567 | 0.79 | HMGCR (0.49) | CYP2C9 | |
| SCHEMBL9577625 | 0.79 | HMGCR (0.39) | CYP2C9MMP12MEN1KMT2A | |
| SCHEMBL9749704 | 0.75 | PTGS2 (0.32) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL9749709 | 0.75 | PTGS2 (0.32) | ALDH1A1LMNAMAPTHTTHPGD | |
| SCHEMBL10408051 | 0.73 | HMGCR (0.35) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL9845366 | 0.73 | HMGCR (0.35) | ALDH1A1CYP2C9MAPTKDM4EHPGD | |
| SCHEMBL10408048 | 0.73 | HMGCR (0.35) | ALDH1A1CYP1A2CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL9577632 | 0.72 | LMNA (0.39) | MTNR1AMTNR1BL3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183924-A | Anticholesterol agents, antithrombotics, fungicides | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-02-02 | — | — | US | disclosed |
| US-5082859-A | Anticholesterol, anticoagulant, fungicide | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-01-21 | — | — | US | disclosed |