Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589520 | 0.98 | TSHR (0.51) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL131571 | 0.95 | LMNA (0.47) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9005002 | 0.92 | LMNA (0.45) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL10942655 | 0.91 | ELANE (0.50) | LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9004805 | 0.90 | TP53 (0.47) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL1194007 | 0.86 | TSHR (0.51) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL2808852 | 0.85 | LMNA (0.41) | TSHRTP53PLA2G4BLMNACES2 | |
| SCHEMBL7638637 | 0.85 | LMNA (0.55) | LMNAALDH1A1CES2CES1 | |
| SCHEMBL11345805 | 0.84 | TSHR (0.50) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL83075 | 0.84 | TSHR (0.49) | TSHRTP53PLA2G4BRARBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521112-A1 | POLYMERIC MIXTURES AND PROCESS THEREFOR. | MINNESOTA MINING & MFG (US) | 1993-01-07 | — | — | EP | disclosed |
| WO-1992003483-A1 | POLYMERIC MIXTURES AND PROCESS THEREFOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-05 | — | — | WO | disclosed |