Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131571 | 0.97 | LMNA (0.47) | LMNATSHRTP53CES2CES1 | |
| SCHEMBL9577653 | 0.92 | TSHR (0.54) | LMNATSHRTP53CES2CES1 | |
| SCHEMBL10942655 | 0.92 | ELANE (0.50) | LMNAL3MBTL1SMN1; SMN2MAPTGAA | |
| SCHEMBL7589520 | 0.90 | TSHR (0.51) | LMNATSHRTP53CES2CES1 | |
| SCHEMBL9004805 | 0.88 | TP53 (0.47) | LMNATSHRTP53PLA2G4BSMN1; SMN2 | |
| SCHEMBL23238 | 0.88 | PGR (0.52) | LMNATSHRCES2CES1L3MBTL1 | |
| SCHEMBL5168028 | 0.88 | PGR (0.52) | LMNATSHRCES2CES1L3MBTL1 | |
| SCHEMBL2808852 | 0.87 | LMNA (0.41) | LMNATSHRTP53CES2CES1 | |
| SCHEMBL7638637 | 0.86 | LMNA (0.55) | LMNACES2CES1L3MBTL1TDP1 | |
| Benzene SCHEMBL28162079 | 0.86 | PGR (0.50) | LMNATSHRCES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510539-A | LIQUID KETALS; LONG DARK STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401166-B1 | Nitrogen-containing titanocenes and their use | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| EP-0401165-B1 | New oxygen-containing titanocenes and their use | CIBA GEIGY AG (CH) | 1994-11-30 | — | — | EP | disclosed |
| US-5306600-A | Oxygen-containing titanocenes, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0318894-B1 | Titanocenes, their use and N-substituted pyrroles | CIBA GEIGY AG (CH) | 1994-02-16 | — | — | EP | disclosed |
| EP-0318893-B1 | Titanocenes, their use and N-substituted fluoroanilines | CIBA GEIGY AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| EP-0255486-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5192642-A | Photoinitiators for addition photopolymerization, coatings | CIBA-GEIGY CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0256981-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |
| US-5068371-A | Photoinitiators for polymerization | CIBA-GEIGY CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0401166-A2 | Nitrogen-containing titanocenes and their use | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |
| EP-0401165-A1 | New oxygen-containing titanocenes and their use | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |
| US-4970136-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0242330-B1 | LIQUID BLEND OF PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| US-4857654-A | Titanocenes and their use | CIBA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0318894-A2 | Titanocenes, their use and N-substituted pyrroles | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0256981-A2 | Titanocenes and their use | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |
| EP-0242330-A1 | Liquid blend of photoinitiators | CIBA-GEIGY AG (CH) | 1987-10-21 | — | — | EP | disclosed |