SCHEMBL9577660

SCHEMBL9577660

CC(C)(C)C1CCC(N2C(=O)C=CC2=O)CC1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TRPV6 Q9H1D0 2/20 0.38
OPRL1 P41146 9/20 0.37
OPRM1 P35372 8/20 0.37
OPRK1 P41145 7/20 0.37
DGAT1 O75907 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
GLA P06280 1/20 0.33
OGFRL1 Q5TC84 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346218 0.88 ALDH1A1 (0.35) OPRL1OPRM1OPRK1DGAT1ALDH1A1
SCHEMBL209765 0.82 ALDH1A1 (0.46) MEN1KMT2AALDH1A1POLB
SCHEMBL3414903 0.82 ALDH1A1 (0.46) MEN1KMT2AALDH1A1POLB
SCHEMBL26023630 0.82 GSK3A (0.32)
SCHEMBL7226920 0.77 ALDH1A1 (0.39) MEN1KMT2AOPRL1OPRM1OPRK1
SCHEMBL15477998 0.77 ALDH1A1 (0.39) MEN1KMT2AOPRL1OPRM1OPRK1
SCHEMBL20842702 0.76 ALDH1A1 (0.41) MEN1KMT2AOPRL1OPRM1OPRK1
SCHEMBL25582124 0.76 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL20989861 0.75 ALDH1A1 (0.38) KMT2AOPRL1OPRM1OPRK1ALDH1A1
SCHEMBL209046 0.73 ALDH1A1 (0.48) KMT2AOPRL1OPRM1OPRK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0283975-B1 COMPATIBLE BLENDS OF POLYCARBONATE AND METHYL METHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1993-04-21 EP disclosed
US-5061558-A METHACRYLATE PROTECTIVE COATING CONTAINING A UV-ABSORBER FOR POLYCARBONATE ROHM GMBH CHEMISCHE FABRIK (DE) 1991-10-29 US disclosed
US-4950716-A RADIATION TRANSPARENT ROHM GMBH CHEMISCHE FABRIK (DE) 1990-08-21 US disclosed