Amaranth

Amaranth

SCHEMBL9577797

O=S(=O)(O)c1ccc2c(N=Nc3ccc(S(=O)(=O)O)c4ccccc34)c(O)c(S(=O)(=O)O)cc2c1.[NaH]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.98
MEN1 O00255 1/20 0.98
KMT2A Q03164 1/20 0.98
TDP1 Q9NUW8 1/20 0.98
CYP1A2 P05177 6/20 0.78
ALDH1A1 P00352 4/20 0.78
HIF1A Q16665 3/20 0.78
CYP2C9 P11712 2/20 0.57
TSHR P16473 1/20 0.57
PTPRA P18433 1/20 0.57
PTPRB P23467 1/20 0.57
CYP2C19 P33261 1/20 0.57
RAPGEF4 Q8WZA2 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CTRB1 P17538 1/20 0.56
ENPP2 Q13822 4/20 0.56
MAPK1 P28482 2/20 0.53
DNASE1L3 Q13609 1/20 0.53
MPL P40238 3/20 0.48
CTRC Q99895 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amaranth SCHEMBL27515187 1.00 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL185412 1.00 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL4807654 1.00 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL473254 1.00 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL1461501 0.99 THRB (0.96) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL29371627 0.99 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL108344 0.99 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL31222692 0.99 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL344622 0.99 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL185414 0.99 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0229191-B1 FLY-ATTRACTIVE COMPOSITION EARTH CHEMICAL CO., LTD. (JP) 1993-06-02 EP disclosed
US-4855133-A Composition for attracting flies EARTH CHEMICAL COMPANY, LIMITED (JP) 1989-08-08 US disclosed
EP-0229191-A1 FLY-ATTRACTIVE COMPOSITION EARTH CHEMICAL CO., LTD. (JP) 1987-07-22 EP disclosed