Amaranth

Amaranth

SCHEMBL344622

O=S(=O)(O)c1ccc2c(N=Nc3ccc(S(=O)(=O)O)c4ccccc34)c(O)c(S(=O)(=O)O)cc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
CYP1A2 P05177 7/20 0.79
ALDH1A1 P00352 4/20 0.79
HIF1A Q16665 3/20 0.79
CYP2C9 P11712 3/20 0.58
TSHR P16473 1/20 0.58
PTPRA P18433 1/20 0.58
PTPRB P23467 1/20 0.58
CYP2C19 P33261 1/20 0.58
RAPGEF4 Q8WZA2 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CTRB1 P17538 1/20 0.57
ENPP2 Q13822 3/20 0.56
MAPK1 P28482 2/20 0.54
DNASE1L3 Q13609 1/20 0.54
MPL P40238 3/20 0.49
CTRC Q99895 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amaranth SCHEMBL29371627 1.00 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL108344 1.00 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL185414 1.00 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL31222692 1.00 THRB (1.00) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL473254 0.99 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL27515187 0.99 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL185412 0.99 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL4807654 0.99 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL9577797 0.99 THRB (0.98) THRBMEN1KMT2ATDP1CYP1A2
Amaranth SCHEMBL1461501 0.98 THRB (0.96) THRBMEN1KMT2ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 EP claimed
EP-3001190-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, Inc. (JP) 2016-03-30 EP claimed
EP-2543706-A2 Stabilizer of color former and use thereof ARKRAY, Inc. (JP) 2013-01-09 EP claimed
US-8273577-B2 Method for detecting phenothiazine-derivative color and color-developer reagent used therein ARKRAY, INC. (JP) 2012-09-25 US claimed
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF ARKRAY, INC. (JP) 2011-01-20 US claimed
EP-2270105-A1 STABILIZER FOR COLOR DEVELOPER AND USE THEREOF ARKRAY, Inc. (JP) 2011-01-05 EP claimed
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, INC. (JP) 2010-05-06 US claimed
EP-2108952-A1 METHOD FOR DETECTION OF PHENOTHIAZINE DERIVATIVE DYE, AND COLOR-DEVELOPER REAGENT FOR USE IN THE METHOD Arkray, Inc. (JP) 2009-10-14 EP claimed
US-6866867-B2 Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose J. RETTENMAIER & SOEHNE GMBH + CO. KG (DE) 2005-03-15 US claimed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 US claimed
US-3966574-A FD & C DYES SCM CORPORATION (US) 1976-06-29 US claimed
JP-6092024-A None JP disclosed
US-20250019555-A1 INK COMPOSITION FOR SURFACE PRINTING ON COSMETICS, AND METHOD FOR SURFACE PRINTING ON COSMETICS BY USING SAME ACTIVON CO., LTD. (KR) 2025-01-16 US disclosed
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 EP disclosed
US-10976258-B2 Porous planar cell capture system and method of use CHARLES RIVER LABORATORIES, INC. (US) 2021-04-13 US disclosed
EP-0078544-A1 Reagent and process for the detection of a critical water content in hydraulic fluids, especially brake fluids LUCAS INDUSTRIES public limited company (GB) 1983-05-11 EP disclosed
US-4084983-A ALUMINUM FLAKES ON A COATING OF ALUMINUM HYDROXIDE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-04-18 US disclosed
US-3947575-A Peptides as argiotensin converting enzyme inhibitors E. R. SQUIBB & SONS, INC. (US) 1976-03-30 US disclosed
US-3934973-A Finely divided colorants ALLIED CHEMICAL CORPORATION (US) 1976-01-27 US disclosed
US-3931442-A Temporary modification of a pattern mask for use in forming a color CRT screen and a process for modifying the same GTE SYLVANIA INCORPORATED (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN TH, TYR, HPD THRB 1943/4885MEN1 4351/4885KMT2A 2700/4885
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF TYR, CRYZ, MITF THRB 4885/4885MEN1 1993/4885KMT2A 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.