⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611404 | 0.81 | — | — | |
| SCHEMBL1762287 | 0.78 | THRB (0.31) | — | |
| SCHEMBL11068870 | 0.77 | — | — | |
| SCHEMBL10650611 | 0.75 | — | — | |
| SCHEMBL1147257 | 0.72 | — | — | |
| SCHEMBL11043992 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL11151710 | 0.71 | — | — | |
| SCHEMBL11365058 | 0.68 | — | — | |
| SCHEMBL29895325 | 0.66 | — | — | |
| SCHEMBL10784399 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225792-B1 | BLENDS OF FLUOROPLASTICS AND FLUOROELASTOMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5051479-A | Tetrafluoroethylene copolymer with a perfluoro(alkyl vinyl ether) for extrusion | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| US-4713418-A | CURABLE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| US-4676932-A | Synthesis of 1-haloestradiols | THE UNIVERSITY OF NEW MEXICO (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0225792-A2 | Blends of fluoroplastics and fluoroelastomers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-16 | — | — | EP | disclosed |