Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872019 | 0.82 | LMNA (0.46) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL22535019 | 0.80 | KMT2A (0.47) | KMT2ALMNAMAPTMEN1KDM4E | |
| SCHEMBL17872151 | 0.74 | KMT2A (0.44) | KMT2ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL13221969 | 0.74 | ALDH1A1 (0.48) | KMT2ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL9577345 | 0.74 | CYP2C19 (0.41) | KMT2ALMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL496468 | 0.73 | KMT2A (0.50) | KMT2ALMNAHPGDTSHRCYP3A4 | |
| SCHEMBL4949590 | 0.71 | KMT2A (0.53) | KMT2ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL2318407 | 0.71 | KCNA5 (0.47) | KMT2ASMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL1395452 | 0.71 | KMT2A (0.52) | KMT2AMAPTMEN1NPSR1L3MBTL1 | |
| SCHEMBL7636997 | 0.71 | KMT2A (0.52) | KMT2ALMNAALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |