Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412477 | 0.82 | FFAR1 (0.45) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL10473953 | 0.82 | TDP1 (0.37) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL276451 | 0.79 | — | — | |
| SCHEMBL4440354 | 0.78 | LDHA (0.38) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL8529554 | 0.77 | HMGCR (0.36) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL5671030 | 0.77 | KDM4E (0.61) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL9009508 | 0.77 | TDP1 (0.47) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL52091 | 0.77 | HMGCR (0.43) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL9298951 | 0.77 | HMGCR (0.43) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL502185 | 0.75 | TDP1 (0.32) | HMGCRCHRM1TBXA2RADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376859-B1 | METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | claimed |