Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5904257 | 0.81 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL9577916 | 0.77 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL4440354 | 0.75 | LDHA (0.38) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL52091 | 0.74 | HMGCR (0.43) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL9298951 | 0.74 | HMGCR (0.43) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL16411389 | 0.72 | HMGCR (0.34) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL31555508 | 0.72 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL27761178 | 0.72 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL16465223 | 0.71 | ACLY (0.35) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL6558430 | 0.70 | LDHA (0.38) | LDHASRR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584818-B1 | Aqueous coating compositions comprising a dispersion of a polyurethane resin, process for their preparation and their use | HERBERTS & CO GMBH (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0584818-A1 | Aqueous polyuretane dispersions, process for their preparation and their use in aqueous coating compositions | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1994-03-02 | — | — | EP | disclosed |