Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130395 | 0.94 | LMNA (0.44) | LMNA | |
| SCHEMBL35169 | 0.94 | LMNA (0.44) | LMNA | |
| SCHEMBL9717789 | 0.90 | LMNA (0.43) | LMNA | |
| Ammonia Solution, Strong SCHEMBL819686 | 0.90 | LMNA (0.43) | LMNA | |
| Ammonia Solution, Strong SCHEMBL5798615 | 0.90 | LMNA (0.43) | LMNA | |
| Water SCHEMBL1968372 | 0.90 | LMNA (0.43) | LMNA | |
| Hydrochloric Acid SCHEMBL524172 | 0.90 | LMNA (0.43) | LMNA | |
| SCHEMBL30297175 | 0.90 | LMNA (0.43) | LMNA | |
| Ammonia Solution, Strong SCHEMBL6654953 | 0.88 | LMNA (0.46) | LMNA | |
| Hydrochloric Acid SCHEMBL18837952 | 0.88 | LMNA (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574381-A1 | SILANE PRIMER COMPOSITION. | AMERICAN STANDARD INC (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992010531-A1 | SILANE PRIMER COMPOSITION | AMERICAN STANDARD INC. (US) | 1992-06-25 | — | — | WO | disclosed |