Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589899 | 0.84 | TNFRSF1A (0.55) | MEN1KMT2AGAATNFRSF1AALDH1A1 | |
| SCHEMBL11229435 | 0.84 | TNFRSF1A (0.55) | MEN1KMT2AGAATNFRSF1AALDH1A1 | |
| SCHEMBL8751538 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL10724006 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL9855739 | 0.75 | GAA (0.57) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL1187217 | 0.75 | MEN1 (0.57) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL10964373 | 0.75 | TNFRSF1A (0.55) | MEN1KMT2AGAATNFRSF1AALDH1A1 | |
| SCHEMBL4729051 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL5507011 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2AGAAALDH1A1TSHR | |
| Benzene SCHEMBL9807217 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210118-A | Phenyl-3-Pyrazolidinones | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | claimed |