SCHEMBL11229435

SCHEMBL11229435

CC(C)(C)c1cc(CC=Cc2ccccc2)cc(C(C)(C)C)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 1/20 0.55
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GAA P10253 2/20 0.49
PTGS1 P23219 5/20 0.47
PTGS2 P35354 5/20 0.47
ALOX5 P09917 3/20 0.46
ALDH1A1 P00352 6/20 0.44
MAPT P10636 4/20 0.44
TSHR P16473 3/20 0.44
CYP3A4 P08684 3/20 0.44
MAPK1 P28482 3/20 0.44
CYP1A2 P05177 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
HIF1A Q16665 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
USP2 O75604 1/20 0.44
CYP2D6 P10635 1/20 0.44
LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589899 1.00 TNFRSF1A (0.55) TNFRSF1AMEN1KMT2AGAAPTGS1
SCHEMBL11231344 0.87 TNFRSF1A (0.42) TNFRSF1AMEN1KMT2AGAAPTGS1
SCHEMBL11231349 0.87 TNFRSF1A (0.42) TNFRSF1AMEN1KMT2AGAAPTGS1
SCHEMBL11579939 0.85 ALDH1A1 (0.45) TNFRSF1AMEN1KMT2AGAAALDH1A1
SCHEMBL11579944 0.85 ALDH1A1 (0.45) TNFRSF1AMEN1KMT2AGAAALDH1A1
SCHEMBL9579489 0.84 MEN1 (0.51) TNFRSF1AMEN1KMT2AGAAPTGS1
SCHEMBL10724006 0.81 ALDH1A1 (0.57) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL8751538 0.81 ALDH1A1 (0.57) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL11579980 0.81 TNFRSF1A (0.48) TNFRSF1AMEN1KMT2AGAAPTGS1
SCHEMBL11575696 0.81 TNFRSF1A (0.48) TNFRSF1AMEN1KMT2AGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082814-A DI-TERT-BUTYL-CINNAMYL PHENOLS, DI-TERT-BUTYL-DIHYDROCINNAMYL PHENONLS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1978-04-04 US claimed
US-3973040-A Certain cinnamyl phenols as growth inhibitors for mosquito larvae THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-08-03 US claimed
US-9957209-B2 Use of quinone methides as antipolymerants for vinylic monomers ECOLAB USA INC. (US) 2018-05-01 US disclosed
US-20160289147-A1 USE OF QUINONE METHIDES AS ANTIPOLYMERANTS FOR VINYLIC MONOMERS ECOLAB USA INC. 2016-10-06 US disclosed
US-4366331-A Process for production of 2,6-di-tert-alkenyl phenols THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-12-28 US disclosed
US-4082814-A DI-TERT-BUTYL-CINNAMYL PHENOLS, DI-TERT-BUTYL-DIHYDROCINNAMYL PHENONLS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1978-04-04 US disclosed
US-4049722-A Polybutyl-2-cinnamylphenols as insect anti-procreants THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-09-20 US disclosed
US-3973040-A Certain cinnamyl phenols as growth inhibitors for mosquito larvae THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-08-03 US disclosed
US-3959489-A Polybutyl-2-cinnamylphenols as insect anti-procreants THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289147-A1 USE OF QUINONE METHIDES AS ANTIPOLYMERANTS FOR VINYLIC MONOMERS SQOR, NQO1, VAT1 TNFRSF1A 1388/4885MEN1 863/4885KMT2A 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.