Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 3/20 | 0.49 |
| ▸ | RAC1 | P63000 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514151 | 0.87 | CDC42 (0.40) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| SCHEMBL10513326 | 0.77 | CA12 (0.41) | NPC1RAB9AHTTLMNANFKB1 | |
| SCHEMBL9088673 | 0.74 | CDC42 (0.60) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| Fumaric Acid SCHEMBL9432148 | 0.70 | ALDH1A1 (0.38) | GABRA1GABRG2GABRB3GABRA3ALDH1A1 | |
| SCHEMBL11603510 | 0.69 | CDC42 (0.60) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| SCHEMBL11265451 | 0.69 | CDC42 (0.60) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| Biphenyl SCHEMBL27297012 | 0.68 | CDC42 (0.46) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| SCHEMBL10934380 | 0.68 | CDC42 (0.59) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| SCHEMBL10934382 | 0.67 | CDC42 (0.45) | CDC42RAC1PTGS2PTGS1CHRM3 | |
| SCHEMBL11602554 | 0.67 | CDC42 (0.48) | CDC42RAC1PTGS2PTGS1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330283-A1 | Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1989-08-30 | — | — | EP | claimed |
| JP-5301875-A | — | — | None | — | — | JP | disclosed |
| JP-H05301875-A | NEW 5,6-DIPHENYL-1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBOXYLIC ACID DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1993-11-16 | — | — | JP | disclosed |
| CN-1036956-A | New 5,6-phenylbenzene-1, the preparation method of 2-dihydro-3H-pyrrolo-[1,2-a] pyrroles-1-carboxylic acid derivative | HISAMITSU PHARMACEUTICAL CO (JP) | 1989-11-08 | — | — | CN | disclosed |
| EP-0330283-A1 | Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330283-A1 | Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330283-A1 | Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1989-08-30 | — | — | EP | disclosed |