Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.73 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL7682688 | 0.98 | AKR1C3 (0.71) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| SCHEMBL15714152 | 0.86 | AKR1C3 (0.73) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| SCHEMBL21617913 | 0.85 | AKR1C3 (0.48) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| SCHEMBL11281357 | 0.85 | PTGS1 (0.53) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL253759 | 0.84 | AKR1C3 (1.00) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| SCHEMBL10536961 | 0.84 | AKR1C3 (0.75) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| SCHEMBL226124 | 0.83 | HTT (0.63) | LMNAKDM4ESMN1; SMN2MAPTNPC1 | |
| SCHEMBL6480428 | 0.83 | CYP1A2 (0.74) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL503709 | 0.83 | PTGS1 (0.97) | PTGS1AKR1C3AKR1C2LMNACYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL9504321 | 0.83 | PTGS1 (0.73) | PTGS1AKR1C3AKR1C2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145993-A | Process for preparing D-2-(6-methoxy-2-naphthyl)-propionic acid and intermediate thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-09-08 | — | — | US | claimed |
| EP-0011925-B1 | NAPHTHALENE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0011925-A1 | Naphthalene derivatives, a process for their preparation and their use in anti-inflammatory pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1980-06-11 | — | — | EP | claimed |
| US-5179208-A | Analgesics | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-01-12 | — | — | US | disclosed |
| US-5179208-A | Analgesics | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-01-12 | — | — | US | disclosed |
| US-5145993-A | Process for preparing D-2-(6-methoxy-2-naphthyl)-propionic acid and intermediate thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-09-08 | — | — | US | disclosed |
| US-5145993-A | Process for preparing D-2-(6-methoxy-2-naphthyl)-propionic acid and intermediate thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-09-08 | — | — | US | disclosed |
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4028366-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4011339-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4005093-A | ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-01-25 | — | — | US | disclosed |