Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998251 | 0.98 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15478764 | 0.98 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28998257 | 0.98 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7520391 | 0.98 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL255879 | 0.94 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5144090 | 0.89 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25426 | 0.89 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22440464 | 0.88 | TSHR (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1981523 | 0.87 | THRB (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22554404 | 0.87 | TSHR (0.83) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2628779-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| EP-3130651-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-15 | — | — | EP | disclosed |
| WO-2017020998-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | WO | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| WO-2013124040-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
| EP-2628779-A2 | Liquid-crystalline medium | Merck Patent GmbH (DE) | 2013-08-21 | — | — | EP | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-5264523-A | Silane coupler | DAIKIN INDUSTRIES, LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-3971884-A | Ethylene-vinyl acetate silicone rubber adherent laminates and method of production | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | TSHR 4041/4885THRB 851/4885POLB 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.