Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867845 | 0.82 | ADRA1A (1.00) | ADRA1ADRD2DRD3ACHEMAOA | |
| Hydrochloric Acid SCHEMBL10447053 | 0.80 | ADRA1A (0.95) | ADRA1ADRD2DRD3ACHEMAOA | |
| SCHEMBL31143007 | 0.72 | ADRA1A (0.78) | ADRA1ADRD2DRD3ACHEMAOA | |
| SCHEMBL24734855 | 0.69 | ADRA1A (1.00) | ADRA1ADRD2DRD3HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL8669188 | 0.68 | ADRA1A (0.96) | ADRA1ADRD2DRD3HTR1DHTR1B | |
| Bromide SCHEMBL25243558 | 0.68 | ADRA1A (0.96) | ADRA1ADRD2DRD3HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL30861222 | 0.68 | ADRA1A (0.96) | ADRA1ADRD2DRD3HTR1DHTR1B | |
| SCHEMBL24650805 | 0.67 | ADRA1A (0.68) | ADRA1ADRD2DRD3ACHE | |
| SCHEMBL8542873 | 0.67 | ADRA1A (0.63) | ADRA1ADRD2DRD3ACHE | |
| SCHEMBL24650787 | 0.66 | ADRA1A (0.66) | ADRA1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5201978-A | — | — | None | — | — | JP | disclosed |
| JP-H05201978-A | N-(4,7-DIMETHOXY-2-INDANYL)-1-(PHENYLCARBONYL)-N-PROPYL-4-PIRERIDINE METHANEAMINE DERIVATIVE, ITS PREPARATION AND ITS APPLICATION TO PHARMACEUTICALS | SYNTHELABO SA | 1993-08-10 | — | — | JP | disclosed |