Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.62 |
| ▸ | NAAA | Q02083 | 6/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644860 | 0.85 | NAAA (0.68) | FAAHNAAA | |
| SCHEMBL11276769 | 0.79 | SMN1; SMN2 (0.66) | PTGS1AKR1C3AKR1C2SMN1; SMN2RAB9A | |
| SCHEMBL22423314 | 0.77 | FAAH (0.55) | FAAHNAAAHSD17B10SMN1; SMN2MAPK10 | |
| SCHEMBL19612567 | 0.76 | FAAH (1.00) | FAAHNAAA | |
| SCHEMBL9580282 | 0.75 | POLB (0.59) | PTGS1AKR1C3AKR1C2MAPTLMNA | |
| SCHEMBL21095220 | 0.74 | PTGS1 (0.58) | FAAHPTGS1AKR1C3AKR1C2HSD17B10 | |
| SCHEMBL19612661 | 0.73 | FAAH (1.00) | FAAHNAAAKDM4E | |
| SCHEMBL19612588 | 0.73 | FAAH (1.00) | FAAHNAAA | |
| SCHEMBL20644859 | 0.73 | KDM4E (0.41) | FAAHNAAAPTGS1AKR1C3AKR1C2 | |
| SCHEMBL5967331 | 0.73 | PTGS1 (0.48) | FAAHNAAAPTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179208-A | Analgesics | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-01-12 | — | — | US | claimed |
| US-5145993-A | Process for preparing D-2-(6-methoxy-2-naphthyl)-propionic acid and intermediate thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-09-08 | — | — | US | claimed |
| US-5179208-A | Analgesics | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-01-12 | — | — | US | disclosed |
| US-5145993-A | Process for preparing D-2-(6-methoxy-2-naphthyl)-propionic acid and intermediate thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-09-08 | — | — | US | disclosed |