SCHEMBL9580423

SCHEMBL9580423

CC1(C)CC(N(N)C(=O)C(=O)NCCCCCCCCCCNC(=O)C(=O)N(N)C2CC(C)(C)N(O)C(C)(C)C2)CC(C)(C)N1O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
EPHX2 P34913 8/20 0.31
POLB P06746 1/20 0.31
NAAA Q02083 1/20 0.31
MAPK8 P45983 1/20 0.31
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9580438 0.82 HPGD (0.31) HPGDSMN1; SMN2NPSR1
SCHEMBL9200819 0.82 GAA (0.37) HPGDSMN1; SMN2NPSR1ALOX15LMNA
SCHEMBL9580344 0.81
SCHEMBL9580305 0.79 GAA (0.37) KDM4EGAAEPHX2
SCHEMBL8161429 0.68 GAA (0.41) HPGDSMN1; SMN2NPSR1LMNAKDM4E
SCHEMBL21103465 0.67 GAA (0.40) HPGDSMN1; SMN2NPSR1LMNAKDM4E
SCHEMBL18901300 0.66 GAA (0.43) ALDH1A1ALOX15KDM4EGAA
SCHEMBL16978099 0.64 NAAA (0.49) KDM4EGAAPOLBNAAAGNAI3
SCHEMBL9208678 0.64 EPHX2 (0.36) HPGDSMN1; SMN2NPSR1ALDH1A1LMNA
SCHEMBL2963209 0.63 GAA (0.40) KDM4EGAAGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5213897-A Curable coating compositions containing an N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazide ELF ATOCHEM NORTH AMERICA, INC. 1993-05-25 US disclosed