Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516969 | 1.00 | TRPV1 (0.39) | TRPV1HTR2AHTR2CHTR2BCACNA1B | |
| SCHEMBL9516964 | 1.00 | TRPV1 (0.39) | TRPV1HTR2AHTR2CHTR2BCACNA1B | |
| SCHEMBL9516957 | 1.00 | TRPV1 (0.39) | TRPV1HTR2AHTR2CHTR2BCACNA1B | |
| SCHEMBL9580537 | 0.85 | NPSR1 (0.38) | HTR2AHTR2CHTR2BCACNA1FCACNA1D | |
| SCHEMBL9580409 | 0.80 | HPGD (0.44) | TRPV1CETPCNR2PPARGPPARD | |
| SCHEMBL9580563 | 0.80 | HPGD (0.44) | TRPV1CETPCNR2PPARGPPARD | |
| SCHEMBL9580418 | 0.80 | HPGD (0.44) | TRPV1CETPCNR2PPARGPPARD | |
| SCHEMBL9580565 | 0.80 | HPGD (0.44) | TRPV1CETPCNR2PPARGPPARD | |
| SCHEMBL9580554 | 0.78 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BCACNA1FCACNA1D | |
| SCHEMBL9516614 | 0.77 | NPSR1 (0.40) | HTR2AHTR2CHTR2BCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |