Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580527 | 0.92 | HTR2A (0.43) | ALDH1A1KCNN4CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9580506 | 0.79 | SLC6A3 (0.46) | — | |
| SCHEMBL9580509 | 0.79 | SLC6A3 (0.46) | — | |
| SCHEMBL9516957 | 0.78 | TRPV1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2A | |
| SCHEMBL9516969 | 0.78 | TRPV1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2A | |
| SCHEMBL9580461 | 0.78 | TRPV1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2A | |
| SCHEMBL9516964 | 0.78 | TRPV1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CHTR2A | |
| SCHEMBL9580537 | 0.77 | NPSR1 (0.38) | ALDH1A1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9515220 | 0.76 | HTR2C (0.49) | HTR2AHTR2CHTR2BTRPM5 | |
| SCHEMBL9515225 | 0.76 | HTR2C (0.49) | HTR2AHTR2CHTR2BTRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |