SCHEMBL9580558

SCHEMBL9580558

CC(C)CNC(=S)/C=C/C=C/C1CC1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.39
SLC6A4 P31645 11/20 0.34
SLC6A3 Q01959 11/20 0.34
SLC6A2 P23975 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516730 1.00 HPGD (0.39) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9516724 1.00 HPGD (0.39) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9580565 0.87 HPGD (0.44) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9580563 0.87 HPGD (0.44) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9580418 0.87 HPGD (0.44) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9580409 0.87 HPGD (0.44) HPGDSLC6A4SLC6A3SLC6A2TSHR
SCHEMBL9516663 0.83 SLC6A3 (0.35) SLC6A4SLC6A3SLC6A2
SCHEMBL9516672 0.83 SLC6A3 (0.35) SLC6A4SLC6A3SLC6A2
SCHEMBL9580561 0.75 NOS3 (0.39) SLC6A4SLC6A3SLC6A2
SCHEMBL9580562 0.75 NOS3 (0.39) SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5202356-A Insecticides, miticides THE WELLCOME FOUNDATION LIMITED (GB) 1993-04-13 US disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed