Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580586 | 1.00 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL9580590 | 1.00 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL10888269 | 0.91 | ABCC9 (0.67) | ABCC9ABCB1 | |
| SCHEMBL10888227 | 0.89 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL10888239 | 0.89 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL10888235 | 0.89 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL9398463 | 0.88 | ABCC9 (0.69) | ABCC9ABCB1 | |
| SCHEMBL10885395 | 0.86 | ABCC9 (0.72) | ABCC9ABCB1 | |
| SCHEMBL10887155 | 0.85 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL9273381 | 0.83 | ABCC9 (0.78) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076075-B1 | PHARMACEUTICALLY ACTIVE BENZOPYRAN COMPOUNDS | BEECHAM GROUP PLC (GB) | 1986-11-20 | — | — | EP | claimed |
| JP-5310729-A | — | — | None | — | — | JP | disclosed |
| JP-H05310729-A | CHEMICAL INTERMEDIATE | BEECHAM GROUP PLC | 1993-11-22 | — | — | JP | disclosed |
| EP-0120427-B1 | 3,4-Dihydro-thiaoxo-1-pyrrolidinyl-or piperidinyl-ZH-benzo[b]pyrons | BEECHAM GROUP PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4647670-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0093535-B1 | NOVEL CHROMENES AND CHROMANS | BEECHAM GROUP PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4610992-A | Trans-4-(2-thiaoxo-1-pyrrolidinyl or piperidinyl)-2H-benzo[b]pyran-3-ol derivatives useful in treating hypertension | BEECHAM GROUP P.L.C. (GB) | 1986-09-09 | — | — | US | disclosed |
| US-4510152-A | Antihypertensive chromenes and chromans | BEECHAM GROUP P.L.C. (GB) | 1985-04-09 | — | — | US | disclosed |
| US-4446113-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-05-01 | — | — | US | disclosed |
| EP-0093535-A1 | Novel chromenes and chromans | BEECHAM GROUP PLC (GB) | 1983-11-09 | — | — | EP | disclosed |
| EP-0076075-A1 | Pharmaceutically active benzopyran compounds | BEECHAM GROUP PLC (GB) | 1983-04-06 | — | — | EP | disclosed |