Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.55 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580588 | 0.91 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL9580586 | 0.91 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL9580590 | 0.91 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL9398463 | 0.89 | ABCC9 (0.69) | ABCC9ABCB1 | |
| SCHEMBL10885395 | 0.89 | ABCC9 (0.72) | ABCC9ABCB1 | |
| SCHEMBL10888235 | 0.86 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL10887155 | 0.86 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL10888227 | 0.86 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL10888239 | 0.86 | ABCC9 (0.71) | ABCC9ABCB1 | |
| SCHEMBL9354088 | 0.85 | ABCC9 (0.64) | ABCC9ABCB1KCNE1KCNQ1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095316-B1 | PHARMACEUTICALLY ACTIVE AMINOBENZOPYRANS | BEECHAM GROUP PLC (GB) | 1986-12-03 | — | — | EP | claimed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | claimed |
| US-4568692-A | LOWERING BLOOD PRESSURE | BEECHAM GROUP P.L.C. | 1986-02-04 | — | — | US | disclosed |
| US-4481214-A | 4-Acylaminobenzopyrans useful as anti-hypertensive agents | BEECHAM GROUP P.L.C. (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |